Sequential Screen Second Trimester
Test Mnemonic
SEQ2
CPT Codes
- 82105 - QTY (1)
- 82677 - QTY (1)
- 84702 - QTY (1)
- 86336 - QTY (1)
Includes
- Pregnancy-associated plasma protein (PAPP-A)
- Human chorionic gonadotropin (hCG)
- unconjugated estriol (uE3)
- Alpha Fetoprotein (AFP)
- Estriol
- Dimeric Inhibin-A
- Down Syndrome Screening Risk
- Trisomy 18 Screening Risk
- ONTD Screening Risk
- Down Syndrome Age Related Risk
- Trisomy 18 Age Related Risk
- ONTD Age Related Risk
Performing Laboratory
Integrated Genetics/Labcorp
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Serum | SST (Gold) | Ambient | Specimen MUST be drawn between 15.0 - 21.9 weeks gestation. Draw 2 tubes to ensure adequate serum volume. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 7 days |
| Refrigerated | 14 days |
| Frozen | 14 days, 3 freeze/thaw cycles |
Days Performed
Mon - Fri
Turnaround Time
3 - 6 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescence Immunoassay (CLIA) |
Reference Range
Special Info
Specimen MUST be drawn between 15.0 - 21.9 weeks gestation. Draw 2 tubes to ensure adequate serum volume.
Clinical Info
Sequential Screen is a two-part test that screens for fetal Down syndrome, trisomy 18 and open neural tube defects.