C1Q Binding Assay
Test Mnemonic
C1Q2
CPT Codes
- 86332 - QTY (1)
LOINC ®
27831-7
Aliases
- Immune Complex Assay (C1Q)
- Circulating Immune Complex, C1q Binding
Performing Laboratory
ARUP
FDA Category
In Vitro Diagnostic
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Frozen, Critical | CRITICAL FROZEN. Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately in a standard aliquot tube. Separate specimens must be submitted when multiple tests are ordered. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Frozen, Critical | CRITICAL FROZEN. Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately in a standard aliquot tube. Separate specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 hours |
| Frozen | After separation from cells: 2 weeks (Avoid repeated freeze/thaw cycles) |
| Refrigerated | After separation from cells: Unacceptable |
Days Performed
Mon, Thu, Sat
Turnaround Time
3 - 10 days
Methodology
| Name | Description |
|---|---|
| Semi Quantitative Enzyme Linked Immunosorbent Assay |
Reference Range
| Circulating Immune Complex, C1Q Binding | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < or = 3.9 ug Eq/mL |
Special Info
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Non-frozen specimens will be rejected. This test is New York DOH approved.
Clinical Info
Less than or equal to 3.9 µg Eq/mL is considered negative for circulating complement binding immune complexes. Circulating immune complexes may be found without any evident pathology, and positive results do not necessarily implicate the immune complex in a disease process.