Chymotrypsin, Stool




Test Mnemonic

CHYMO

CPT Codes

  • 84311 - QTY (1)

LOINC ®

25375-7

Performing Laboratory

Quest SJC


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 gStoolSterile container Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 g     

Stability

Environmental Condition Description
AmbientUnacceptable
Refrigerated2 weeks
Frozen30 days

Days Performed

Wed

Turnaround Time

4 - 12 days

Methodology

Name Description
Enzymatic 
Spectrophotometry (S) 

Reference Range

Chymotrypsin, Stool
Sex Age From Age To Type Range Range Unit
       Normal2.3 - 51.4U/g

Special Info

Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days before the collection of the stool sample.

Clinical Info

The diagnosis of chronic pancreatitis depends upon the demonstration of functional impairment of the pancreas. Impairment is detemined by several means, two of which are: 1. Direct measurement of exocrine secretion into the duodenum after stimulation by a standard meal or after stimulation by intravenous secretin/pancreozymin.2. The direct measurement of the activities of certain enzymes in feces. Chymotrypsin activity in stool, for example, has been shown lower than normal in patients with pancreatic exocrine insufficiency.