Complement C 2
Test Mnemonic
COMPC2
CPT Codes
- 86160 - QTY (1)
LOINC ®
4484-2
Aliases
- C2 Complement Component
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Frozen, Critical | Allow specimen to clot for one hour at ambient temperature. Then separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. Freeze immediately. Separate specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 hours |
| Refrigerated | After separation from cells: Unacceptable |
| Frozen | After separation from cells: 2 weeks |
Days Performed
Mon, Thu
Turnaround Time
6 - 11 days
Methodology
| Name | Description |
|---|---|
| Radial Immunodiffusion (RID) |
Reference Range
| Complement C 2 | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 1.6 - 4.0 | mg/dL |
Special Info
Unacceptable Conditions: samples left to clot at 2 - 8 degrees C, samples subjected to repeated freeze/thaw cycles, or non-frozen samples. This test is New York DOH approved.
Clinical Info
Decreased C2 levels may be associated with increased susceptibility to infection, systemic lupus erythematosus-like disease, rashes, arthritis, nephritis and with C1-Esterase deficiency. Increased C2 levels are associated with the acute phase response. This is a follow-up test for complement activity screening when CH50 is low or absent and AH50 is normal and high suspicion remains for complement deficiency.