Diazepam & Metabolite
Test Mnemonic
DIAZEP
CPT Codes
- 80346 - QTY (1)
- G0480 - QTY (1)
LOINC ®
3548-5
Aliases
- Valium
Includes
- Diazepam and Nordiazepam
Performing Laboratory
ARUP
FDA Category
Laboratory Developed Test
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tube. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate serum from cells within 2 hours of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Plasma | EDTA (Lavender) | Refrigerated | Do not use plasma separator tubes. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate plasma from cells within 2 hours of collection. | |
| 2 mL | Plasma | Sodium heparin (Green) | Refrigerated | Do not use plasma separator tubes. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate plasma from cells within 2 hours of collection. | |
| 2 mL | Plasma | Potassium oxalate/sodium fluoride (Gray) | Refrigerated | Do not use plasma separator tubes. Timing of specimen collection: Pre-dose (trough) draw at steady state concentration. Separate plasma from cells within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 1 week |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 3 years |
Days Performed
Tue, Fri
Turnaround Time
2 - 8 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
Reference Range
| Diazepam | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| 200 - 1000 ng/mL (based on normal dosage amounts) | |||||
| Nordiazepam | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| 100 - 1500 ng/mL (based on normal dosages) | Years | 99 Years | Critical | > 2500 | ng/mL |
Special Info
Avoid use of serum separator tubes or gels.
Clinical Info
Monitor therapy